Pál, C., Papp, B., Lercher, M. J., Csermely, P., Oliver, S. G. & Hurst, L. D. (2006). Chance and necessity in the evolution of minimal metabolic networks. Nature 440(7084): 667–670. doi:10.1038/nature04568.
Not read. The summary is drawn from the abstract. A reading should check it first.
Why this is here
Adjacent material. A1 said the record’s questions are “amenable to mathematical treatment through … metabolic network constraints” and named no work. This is the standard demonstration that network constraints, with contingency, predict which genes a symbiont loses.