Bohacek, J. & Mansuy, I. M. (2015). Nature Reviews Genetics, 16(11), 641–652.
Not read. The summary is drawn from the abstract or from what the work is standardly cited for. A reading should check it first.
Why this is here
The proponents’ review of the mechanisms. For QUESTION-297.
Read in its place
The work cannot be read here, so the record holds it at second hand.
Jawaid and Mansuy 2019 (LIT-1774, NOTE-1296), by the same senior author four years later. It cites this review (its ref. 3) as the account of germline-dependent transmission, of the tests by artificial insemination, IVF and sperm-RNA injection, and of the MSUS mouse model. It gives the laboratory’s case in short form, updated with 2016–2018 results on enrichment, sperm RNA and human sperm. The LIT summary agrees with what the later review shows. Missing still: the 2015 text itself; its treatment of germline reprogramming and of marks that escape it; its account of DNA methylation and chromatin as carriers, beside RNA; any criteria it set for inter- versus transgenerational effects; whether it answered the critics; and what it said of humans.